This depends on how sterile your protocol requires them to be. First rinse in pH neutral distilled water and remove blood and debris. Use a fresh neutral pH solvent and then a soft brush for the tough cleaning. If you steam autoclave, make sure that you use manufacturer’s instructions for your autoclave (clean neutral pH distilled water), and that your high quality instruments are not mixed with instruments of inferior quality. Impurities from the lower quality instrument can start a corrosive action on your good ones. Be sure that the full drying cycle is used. Overlapping joints may have dampness within the joint, increasing the chance of corrosion. This can be prevented in three ways: assure the full drying cycle is complete, apply silicone grease inside the joint as a protective layer, or by use of an air canister or hair dryer to blow moisture out of overlapping parts. Instruments can also be cleaned ultrasonically but must be immediately rinsed and dried.